When a pharmaceutical company changes an SPC or PIL, a new version is published on medicines.ie. For each version, we show the dates it was published on medicines.ie and the reasons for change.
2 qualitative and QUantitative composition Each tablet contains 2mg of the active ingredient chlorambucil. Each tablet also contains 67.65mg of lactose. For a full list of excipients, see 6.1. 3 pharmaceutical form Film-coated tablet (Tablet) Brown, film-coated, round, biconvex tablets engraved ‘GX EG3’ on one side and ‘L’ on the other. ……………………… 4.3 Contraindications Use in the management of patients with non-malignant disease. Hypersensitivity to chlorambucil or to any of the excipients. …………………………… 6.5. Nature and Contents of Container Leukeran tablets are supplied in amber (Type III) glass bottles with a child resistant polypropylene/ HDPE closure containing 25 or 50 tablets. Not all pack sizes may be marketed 6.6. Instructions for Use/Handling Special precautions for disposal of a used medicinal product or waste materials derived from such medicinal product and other handling of the product
Each tablet contains 2mg of the active ingredient chlorambucil.
Each tablet also contains 67.65mg of lactose.
For a full list of excipients, see 6.1.
Film-coated tablet (Tablet) Brown, film-coated, round, biconvex tablets engraved ‘GX EG3’ on one side and ‘L’ on the other. ……………………… 4.3 Contraindications Use in the management of patients with non-malignant disease. Hypersensitivity to chlorambucil or to any of the excipients. …………………………… 6.5. Nature and Contents of Container Leukeran tablets are supplied in amber (Type III) glass bottles with a child resistant polypropylene/ HDPE closure containing 25 or 50 tablets. Not all pack sizes may be marketed 6.6. Instructions for Use/Handling Special precautions for disposal of a used medicinal product or waste materials derived from such medicinal product and other handling of the product
Brown, film-coated, round, biconvex tablets engraved ‘GX EG3’ on one side and ‘L’ on the other.
………………………
Use in the management of patients with non-malignant disease.
Hypersensitivity to chlorambucil or to any of the excipients.
Leukeran tablets are supplied in amber (Type III) glass bottles with a child resistant polypropylene/ HDPE closure containing 25 or 50 tablets.
Not all pack sizes may be marketed
4.4 Special Warnings and Special Precautions for Use
5.1 Pharmacodynamic Properties
Blood and Lymphatic system disorders:
Very common: leucopenia, neutropenia, thrombocytopenia, panyctopenia
Common: anaemia