When a pharmaceutical company changes an SPC or PIL, a new version is published on medicines.ie. For each version, we show the dates it was published on medicines.ie and the reasons for change.
Section 4.4:
Section 4.4 is updated to include the following: 'Baseline blood pressure should be established and patients should receive the drug lying down. Blood pressure should be closely monitored during administration and at regular intervals until treatment is concluded'.
'The benefit of aerosolised pentamidine therapy in patients at high risk of pneumothorax should be weighed against the clinical consequences of such a manifestation'
Editorial updates also
Section 4.5: Section 4.5 is updated to include the following:
'Foscarnet: risk of hypocalcaemia'.
Section 4.6:
Editorial updates to Section 4.6.
Section 4.7:
The following sentence has been added to Section 4.7: 'Considering the risk of dizziness, one should be careful.'
Section 4.8:
Side effects section updated to improve readability.
Section 10:
Date of revision is now August 2010