|Frequency, type and severity of adverse reactions in children are the same as in adults.|
Gastrointestinal disorders- epigastric pain, nausea, vomiting, malaise, diarrohea- oral mucositis, taste disorders, dry mouth, anorexia.- reversible cases of pancreatitis.
Immune system disorders- angioedema, anaphylactic shock.
Nervous system- peripheral sensory neuropathy, paraesthesia.- headache, convulsions, dizziness.- reports of encephalopathy (e.g. confusion) and subacute cerebellar syndrome (e.g. ataxia, dysathria, gait impairment, nystagmus and tremor) which may resolve with discontinuation of the drug.aseptic meningitis
Psychiatric disorders- psychotic disorders including confusion, hallucinations - depressed mood
Eye disorders- transient vision disorders such as diplopia, myopia, blurred vision, decreased visual acuity, changes in color vision.- Optic neuropathy/neuritis.
Blood and lymphatic system disorders- cases of agranulocytosis, neutropenia and thrombocytopenia have been reported.Hepatobiliary disorders - increase in liver enzymes (AST, ALT, alkaline phosphatase), cholestatic or mixed hepatitis and hepatocellular liver injury, sometimes with jaundice, have been reported. - cases of liver failure requiring liver transplant have been reported in patients treated with metronidazole mostly when used in combination with other antibiotic drugs.
Skin and subcutaneous tissue disorders- rash, pruritus, flushing, urticaria- pustular eruptions
General disorders and administration site conditions- fever