Kalydeco 75 mg and 150 mg film-coated tablets

How to take Kalydeco 

Always take this medicine exactly as your doctor has told you to. Check with your doctor if you are not sure. Your doctor will determine which medicine and dose is right for you.

Kalydeco dosing recommendations are provided below

Dosing recommendations

Monotherapy

The recommended monotherapy dose for patients aged 6 years and older, ≥25 kg is One Kalydeco 150 mg tablet in the morning and One Kalydeco 150 mg tablet in the evening

Kalydeco in combination with tezacaftor/ivacaftor

The recommended combination dose for patients aged 6 years to less than 12 years, <30 kg is One tezacaftor 50 mg/ivacaftor 75 mg tablet in the morning and One Kalydeco 75 mg tablet in the evening.

The recommended combination dose for patients aged 6 years to less than 12 years, ≥30 kg is  One tezacaftor 100 mg/ivacaftor 150 mg tablet in the morning and One Kalydeco 150 mg tablet in the evening.

The recommended combination dose for patients aged 12 years and older is One tezacaftor 100 mg/ivacaftor 150 mg tablet in the morning and One Kalydeco 150 mg tablet in the evening.

Kalydeco in combination with ivacaftor/tezacaftor/elexacaftor

The recommended combination dose for patients aged 12 years and older is Two ivacaftor 75 mg/tezacaftor 50 mg/elexacaftor 100 mg tablets in the morning and One Kalydeco 150 mg tablet in the evening.

Take the morning and evening doses approximately 12 hours apart with food that contains fat