Vertex Pharmaceuticals (Ireland) Limited

Vertex Pharmaceuticals (Ireland) Limited

Symkevi 100 mg/150 mg film coated tablets and 50 mg/ 75 mg film coated tablets

3. How to take Symkevi 

There are different strengths of Symkevi for different age groups. Check you have been given the right dose (below).

The recommended dose for patients aged 6 years to less than 12 years old, weighing less than 30kg is 1 tablet in the morning of tezacaftor 50mg/ivacaftor 75mg and 1 tablet in the evening of ivacaftor 75mg . 

The recommended dose for patients aged 6 years to less than 12 years old, weighing more than or equal to 30kg is 1 tablet in the morning of tezacaftor 100mg/ivacaftor 150mg and 1 tablet in the evening of ivacaftor 150mg . 

The recommended dose for patients aged 12 years and older is 1 tablet in the morning of tezacaftor 100mg/ivacaftor 150mg and 1 tablet in the evening of ivacaftor 150mg . 

Take the tablets about 12 hours apart.

Take both Symkevi and ivacaftor tablets with food that contains fat.