| Xatger 10 mg prolonged release tablets | - |  12/10/16 |  18/10/16 | alfuzosin hydrochloride | Gerard Laboratories |
| Xatral 10mg Prolonged Release Tablets | - | 18/10/19 | 04/03/20 | alfuzosin hydrochloride | SANOFI |
| Xatral 2.5mg Tablets | - | 18/10/19 | 04/03/20 | alfuzosin hydrochloride | SANOFI |
| Xeljanz 10mg film coated tablets | | 05/03/20 | 05/03/20 | Tofacitinib citrate | Pfizer Healthcare Ireland |
| Xeljanz 5mg film coated tablets | | 05/02/20 | 05/02/20 | Tofacitinib citrate | Pfizer Healthcare Ireland |
| XEOMIN (50/100/200) units powder for solution for injection | - | 06/01/20 | 06/01/20 | Botulinum Toxin Type A | Merz Pharma UK Ltd |
| Xeplion 25 mg, 50 mg, 75 mg, 100 mg and 150 mg prolonged-release suspension for injection | - | 23/10/18 | 22/10/18 | Paliperidone palmitate | Janssen Sciences Ireland |
| Xermelo 250 mg film-coated tablets | | 28/11/19 | 28/11/19 | Telotristat ethyl | Ipsen Pharmaceuticals Ltd |
| XGEVA | - | 24/05/19 | 22/11/19 | Denosumab | Amgen Ltd |
| Xigduo 5 mg/850 mg and 5 mg/1,000 mg film coated tablets | - | 25/10/19 | 12/12/19 | Dapagliflozin propanediol monohydrate, Metformin Hydrochloride | AstraZeneca Pharmaceuticals (Ireland) DAC |
| Xofigo 1100 kBq/mL solution for injection | | 21/12/18 | 26/11/19 | radium-223 dichloride | Bayer Limited |
| Xolair 150mg solution for injection | - | 09/08/19 | 29/07/19 | Omalizumab | Novartis Ireland Limited |
| Xolair 75mg solution for injection | - | 09/08/19 | 29/07/19 | Omalizumab | Novartis Ireland Limited |
| Xomolix 2.5mg/ml solution for injection | - | 21/01/19 | 21/01/19 | Droperidol | Kyowa Kirin Ltd |
| Xospata 40 mg film-coated tablets | | 18/02/20 | 14/02/20 | Gilteritinib | Astellas Pharma Co. Ltd |
| Xromi 100 mg/ml oral solution | - | 10/12/19 | 10/12/19 | Hydroxycarbamide | Nova Laboratories Ireland Limited |
| Xtandi 40 mg film-coated tablets | - | 18/02/20 | 18/02/20 | enzalutamide | Astellas Pharma Co. Ltd |
| Xtandi 40 mg soft capsules | - | 10/06/19 | 30/10/18 | enzalutamide | Astellas Pharma Co. Ltd |
| Xultophy 100 units/ml + 3.6 mg/ml solution for injection | - | 04/10/19 | 04/10/19 | Insulin degludec, liraglutide | Novo Nordisk Limited |
| Xydalba 500 mg powder for concentrate for solution for infusion | | 24/01/19 | 24/01/19 | Dalbavancin hydrochloride | Correvio |
| Xylocaine 2% with Adrenaline | - | 09/04/20 | 09/04/20 | Adrenaline tartrate, lidocaine hydrochloride anhydrous | Aspen |
| Xylocaine Spray 10mg | - | 29/05/19 | 16/05/17 | Lidocaine | Aspen |
| Xyrem 500mg/ml oral solution | - | 22/03/19 | 22/03/19 | Sodium oxybate | UCB (Pharma) Ireland Limited |
| Xyzal 0.5mg/ml oral solution | - | 17/08/18 | 17/09/18 | Levocetirizine dihydrochloride | UCB (Pharma) Ireland Limited |
| Xyzal 5mg Tablets | - | 17/08/18 | 17/08/18 | Levocetirizine dihydrochloride | UCB (Pharma) Ireland Limited |
