| Yasminelle | - |  19/12/18 |  19/12/18 | Drospirenone, ethinylestradiol betadex clathrate | Bayer Limited |
| Yaz 0.02mg / 3mg film coated tablets | - | 19/12/18 | 19/12/18 | Drospirenone, ethinylestradiol betadex clathrate | Bayer Limited |
| Yellox 0.9 mg/ml eye drops solution | - | 05/03/18 | 30/08/16 | Bromfenac sodium sesquihydrate | Bausch Health Ireland Ltd. |
| Yentreve | - | 23/08/19 | 23/08/19 | duloxetine hydrochloride | Eli Lilly and Company (Ireland) Limited |
| Yervoy 5mg per ml concentrate for solution for infusion | - | 08/10/19 | 08/10/19 | ipilimumab | Bristol-Myers Squibb Pharma EEIG |
| YESCARTA (axicabtagene ciloleucel) | | 05/06/19 | 05/06/19 | Axicabtagene Ciloleucel | Gilead Sciences Ltd |
| Yondelis 0.25 mg powder for concentrate for solution for infusion/Yondelis 1 mg powder for concentrate for solution for infusion | - | 23/07/18 | 23/07/18 | Trabectedin | Immedica (distributor) |
| Zaltrap 25mg/ml concentrate for solution for infusion | - | 11/11/19 | 12/08/19 | Aflibercept | SANOFI |
| Zanidip 10mg and 20mg Tablets | - | 11/08/17 | - | Lercanidipine Hydrochloride | Recordati Ireland Limited |
| Zanidip 10mg Tablets | - | - | 18/08/17 | Lercanidipine Hydrochloride | Recordati Ireland Limited |
| Zanidip 20mg Tablets | - | - | 18/08/17 | Lercanidipine Hydrochloride | Recordati Ireland Limited |
| Zantac 75 (GSL) | - | 24/07/17 | 30/09/19 | Ranitidine Hydrochloride | Chefaro Ireland Ltd |
| Zantac Effervescent Tablets 150mg | - | 11/09/18 | 11/09/18 | Ranitidine Hydrochloride | GlaxoSmithKline (Ireland) Ltd |
| Zantac Injection 25mg/ml | - | 07/05/19 | 03/05/19 | Ranitidine Hydrochloride | GlaxoSmithKline (Ireland) Ltd |
| Zantac Syrup | - | 22/07/15 | 22/07/15 | Ranitidine Hydrochloride | GlaxoSmithKline (Ireland) Ltd |
| Zantac Tablets 150mg | - | 09/11/16 | 10/11/16 | Ranitidine Hydrochloride | GlaxoSmithKline (Ireland) Ltd |
| Zantac Tablets 300mg | - | 11/11/16 | 11/11/16 | Ranitidine Hydrochloride | GlaxoSmithKline (Ireland) Ltd |
| Zavedos 5mg Powder for Solution for Injection | - | 12/10/18 | 12/10/18 | Idarubicin Hydrochloride | Pfizer Healthcare Ireland |
| Zavesca 100mg hard capsules | - | 30/11/18 | 17/10/18 | Miglustat | Actelion Pharmaceuticals UK Ltd |
| Zavicefta 2g/0.5g powder for concentrate for solution for infusion | | 15/04/19 | 12/04/19 | Ceftazidime Pentahydrate, Avibactam sodium | Pfizer Healthcare Ireland |
| Zebinix 200mg tablets | - | 08/08/19 | 07/08/19 | eslicarbazepine acetate | Eisai Ltd |
| Zebinix 50 mg/ml Oral Suspension | - | 08/08/19 | 07/08/19 | eslicarbazepine acetate | Eisai Ltd |
| Zebinix 800mg tablets | - | 08/08/19 | 07/08/19 | eslicarbazepine acetate | Eisai Ltd |
| Zeffix 100mg Film-Coated Tablets | - | 07/12/18 | 07/12/18 | Lamivudine | GlaxoSmithKline (Ireland) Ltd |
| Zejula 100 mg hard capsules | | 02/07/19 | 02/07/19 | Niraparib tosylate monohydrate | Tesaro UK Limited |
