| Lixiana Film-Coated Tablets | | - |  02/07/19 | Edoxaban tosilate | Daiichi Sankyo Ireland Ltd |
| Loceryl Nail Lacquer | - |  20/06/17 | 06/07/17 | Amorolfine Hydrochloride | Galderma International S.A.S. c/o Galderma (U.K) Ltd. |
| Locoid Cream 0.1% | - | 16/12/19 | 01/03/19 | Hydrocortisone 17-Butyrate | LEO Pharma |
| Locoid Lipocream 0.1% | - | 21/11/19 | 01/03/19 | Hydrocortisone 17-Butyrate | LEO Pharma |
| Locoid Ointment 0.1% | - | 14/08/18 | 01/03/19 | Hydrocortisone 17-Butyrate | LEO Pharma |
| Logynon Tablets | - | 23/05/19 | 22/05/19 | Ethinylestradiol, Levonorgestrel | Bayer Limited |
| Loniten 5 mg Tablets | - | 05/10/16 | 06/10/16 | Minoxidil | Pfizer Healthcare Ireland |
| LONSURF | | 11/09/19 | 11/09/19 | Tipiracil hydrochloride, Trifluridine | Servier Laboratories Ireland Ltd |
| Lonsurf 15mg/6.14mg, 20mg/8.19mg film-coated tablets | | 25/04/17 | 29/08/17 | Tipiracil hydrochloride, Trifluridine | Servier Laboratories Ireland Ltd |
| LOPID 300MG CAPSULES | - | 16/12/19 | 16/12/19 | Gemfibrozil | Pfizer Healthcare Ireland |
| Lopid 600 mg film-coated tablet | - | 16/12/19 | 16/12/19 | Gemfibrozil | Pfizer Healthcare Ireland |
| Lorviqua 25mg & 100mg Film Coated Tablets | | 23/01/20 | 23/01/20 | Lorlatinib | Pfizer Healthcare Ireland |
| Losec Control | - | 09/08/17 | 02/08/17 | omeprazole magnesium | Bayer Limited |
| Losec MUPS 10mg Gastro-resistant Tablets | - | 15/01/19 | 14/01/19 | omeprazole magnesium | AstraZeneca Pharmaceuticals (Ireland) DAC |
| Losec MUPS 20mg Gastro-resistant Tablets | - | 15/01/19 | 14/01/19 | omeprazole magnesium | AstraZeneca Pharmaceuticals (Ireland) DAC |
| Losec MUPS 40mg Gastro-resistant Tablets | - | 15/01/19 | 14/01/19 | omeprazole magnesium | AstraZeneca Pharmaceuticals (Ireland) DAC |
| Lotemax 0.5% Eye Drops, Suspension | - | 09/10/17 | 09/10/17 | Loteprednol Etabonate | Bausch Health Ireland Ltd. |
| Low Centyl K | - | 27/03/19 | 09/07/19 | Bendroflumethiazide, Potassium Chloride | Karo Pharma AB |
| Lucentis 10mg/ml solution for injection in pre-filled syringe | - | 30/10/19 | 30/10/19 | Ranibizumab | Novartis Ireland Limited |
| Lumigan 0.1mg/ml | - | 02/04/19 | 01/02/19 | Bimatoprost | Allergan Ltd |
| LUSTRAL 100 mg film coated tablets | - | 12/11/19 | 12/11/19 | sertraline hydrochloride | Pfizer Healthcare Ireland |
| LUSTRAL 50mg film coated tablets | - | 12/11/19 | 12/11/19 | sertraline hydrochloride | Pfizer Healthcare Ireland |
| Lutinus 100 mg Vaginal Tablets | - | - | 13/01/16 | Progesterone | Ferring Ireland Limited |
| Luveris 75 IU | - | 14/09/18 | 14/09/18 | Lutropin alfa | Merck |
| Lyclear Creme Rinse | - | 03/12/19 | 03/12/19 | Permethrin | Chefaro Ireland Ltd |
