| Activelle | - |  11/03/16 |  16/03/16 | Estradiol Hemihydrate, Norethisterone acetate | Novo Nordisk Limited |
| Angeliq 1 mg / 2 mg film-coated tablets | - | 17/05/17 | 27/10/16 | Drospirenone, Estradiol Hemihydrate | Bayer Limited |
| Divigel 0.1% Gel | - | 03/06/16 | 06/06/16 | Estradiol Hemihydrate | Orion Pharma (Ireland) Ltd |
| Estradot Transdermal Patches | - | 21/05/20 | 29/08/19 | Estradiol Hemihydrate | Novartis Ireland Limited |
| Estrofem 2mg | - | 09/06/17 | 11/03/16 | Estradiol Hemihydrate | Novo Nordisk Limited |
| Evorel 50 Patches | - | 29/04/20 | 28/02/20 | Estradiol Hemihydrate | Theramex Ireland Limited |
| Evorel Conti Patches | - | 29/04/20 | 22/01/20 | Estradiol Hemihydrate, Norethisterone acetate | Theramex Ireland Limited |
| Fematab 1mg film coated tablet | - | 11/09/20 | 11/09/20 | Estradiol Hemihydrate | Mylan IRE Healthcare Limited |
| Fematab 2mg Film-coated tablets | - | 11/09/20 | 11/09/20 | Estradiol Hemihydrate | Mylan IRE Healthcare Limited |
| Femoston 1/10mg film-coated tablet | - | 17/09/20 | 17/09/20 | Dydrogesterone, Estradiol Hemihydrate | Mylan IRE Healthcare Limited |
| Femoston 2/10mg film-coated tablets | - | 17/09/20 | 17/09/20 | Dydrogesterone, Estradiol Hemihydrate | Mylan IRE Healthcare Limited |
| Femoston-Conti 0.5/2.5mg film-coated tablet | - | 20/03/20 | 25/10/19 | Dydrogesterone, Estradiol Hemihydrate | Mylan IRE Healthcare Limited |
| Femoston-conti 1mg/5mg film-coated tablets | - | 20/03/20 | 25/10/19 | Dydrogesterone, Estradiol Hemihydrate | Mylan IRE Healthcare Limited |
| Kliogest 2 mg/1 mg film-coated tablets | - | 26/05/17 | 22/03/16 | Estradiol Hemihydrate, Norethisterone acetate | Novo Nordisk Limited |
| Lenzetto 1.53 mg/spray, Transdermal Spray, Solution | - | 17/09/20 | 17/09/20 | Estradiol Hemihydrate | Gedeon Richter (UK) Ltd |
| Novofem film-coated tablets | - | 07/06/17 | 03/03/16 | Estradiol Hemihydrate, Norethisterone acetate | Novo Nordisk Limited |
| Trisequens | - | 07/06/17 | 20/04/16 | Estradiol Hemihydrate, Norethisterone acetate | Novo Nordisk Limited |
| Vagifem 10 micrograms vaginal tablets | - | 03/04/19 | 18/09/18 | Estradiol Hemihydrate | Novo Nordisk Limited |
| Zoely 2.5 mg/1.5 mg film-coated tablets | | 01/07/20 | 01/07/20 | Estradiol Hemihydrate, Nomegestrol Acetate | Theramex Ireland Limited |
