| Ultibro Breezhaler | - |  09/01/20 |  14/06/19 | Glycopyrronium bromide, Indacaterol maleate | Novartis Ireland Limited |
| Ultiva 1 mg Powder for Concentrate for Solution for Infusion | - | - | 26/03/19 | Remifentanil Hydrochloride | Aspen |
| Ultiva 1 mg, 2 mg, 5 mg powder for concentrate for solution for infusion | - | 26/03/19 | - | Remifentanil Hydrochloride | Aspen |
| Ultiva 2 mg Powder for Concentrate for Solution for Infusion | - | - | 15/10/18 | Remifentanil Hydrochloride | Aspen |
| Ultiva 5 mg Powder for Concentrate for Solution for Infusion | - | - | 15/10/18 | Remifentanil Hydrochloride | Aspen |
| Ultomiris | | 12/07/19 | 12/07/19 | Ravulizumab | Alexion Pharma UK Ltd |
| Ultraproct | - | 10/12/19 | 08/10/19 | Cinchocaine hydrochloride, Fluocortolone caproate, Fluocortolone pivalate | LEO Pharma |
| Ultravist 240 mg/ml Solution for injection (50 ml) | - | 14/03/17 | 13/01/15 | Iopromide | Bayer Limited |
| Ultravist 300 mg/ml Solution for injection (20 ml) | - | 14/03/17 | 13/01/15 | Iopromide | Bayer Limited |
| Ultravist 300 mg/ml Solution for injection (50 ml, 75 ml, 100 ml, 150 ml and 200 ml) | - | 14/03/17 | 14/07/15 | Iopromide | Bayer Limited |
| Ultravist 370 mg/ml Solution for injection (50 ml, 100 ml, 150 ml and 200 ml) | - | 14/03/17 | 13/01/15 | Iopromide | Bayer Limited |
| Uniphyllin Continus Prolonged-Release Tablets | - | 29/08/18 | 29/08/18 | Theophylline Monohydrate | Mundipharma Pharmaceuticals Limited - Formerly Napp Laboratories |
| Uptravi | | 09/08/19 | 08/08/19 | Selexipag | Actelion, a division of Janssen-Cilag International NV |
| Urispas 200mg film-coated tablets | - | 27/11/18 | 09/08/19 | Flavoxate Hydrochloride, Lactose | Recordati Ireland Limited |
| Urografin | - | 08/08/19 | 09/08/19 | Meglumine Amidotrizoate, Sodium Amidotrizoate | Bayer Limited |
| Uromitexan 100 mg/ml Solution for Injection or infusion | - | - | 11/03/19 | Mesna | Baxter Holding B.V. |
| Uromitexan Tablets 400mg | - | - | 11/03/19 | Mesna | Baxter Holding B.V. |
| Uromitexan Tablets 600mg | - | - | 11/03/19 | Mesna | Baxter Holding B.V. |
| Urorec capsules | - | 20/12/19 | 20/12/19 | Silodosin | Recordati Ireland Limited |
| Urostemol Femina | - | 05/04/16 | 11/04/16 | Hop strobili dry extract, Pumpkin seed oil, Sumach bark (fragrant) dry extract | Chefaro Ireland Ltd |
| Urostemol Men capsules | - | 21/07/17 | 24/07/17 | Pumpkin seed, Pumpkin seed oil, Saw palmetto fruit dry extract | Chefaro Ireland Ltd |
| Ursofalk 250mg Hard Capsules | - | 11/01/16 | 13/01/20 | Ursodeoxycholic Acid | DR. FALK PHARMA GMBH |
| Ursofalk 250mg/5ml Suspension | - | 11/08/15 | 05/02/15 | Ursodeoxycholic Acid | DR. FALK PHARMA GMBH |
| Ursofalk 500mg film-coated tablets | - | 27/01/15 | 03/02/15 | Ursodeoxycholic Acid | DR. FALK PHARMA GMBH |
| Vaborem 1 g/1 g powder for concentrate for solution for infusion | | 24/10/19 | 20/11/19 | Meropenem Trihydrate, Vaborbactam | A. Menarini Pharmaceuticals Ireland Ltd |
