| Solu-Medrone 40mg | - |  12/12/19 |  28/11/18 | Methylprednisolone sodium succinate | Pfizer Healthcare Ireland |
| Solu-Medrone 500 mg | - | 12/12/19 | 13/09/19 | Methylprednisolone sodium succinate | Pfizer Healthcare Ireland |
| Somatuline Autogel 60 mg, 90 mg and 120 mg solution for injection in a pre-filled syringe | - | 01/11/19 | 01/11/19 | Lanreotide acetate | Ipsen Pharmaceuticals Ltd |
| Somatuline LA 30mg | - | 12/11/19 | 01/11/19 | Lanreotide acetate | Ipsen Pharmaceuticals Ltd |
| Somavert 10mg, 15mg, 20mg, 25mg and 30mg Powder and Solvent for Solution for Injection | - | 19/11/19 | 08/03/19 | Pegvisomant | Pfizer Healthcare Ireland |
| Soolantra 10 mg/g Cream | - | 24/04/18 | 24/07/19 | Ivermectin | Galderma International S.A.S. c/o Galderma (U.K) Ltd. |
| Sormon Tablets 60mg | - | 16/04/19 | 15/04/19 | Isosorbide Mononitrate | Gerard Laboratories |
| Sotoger 80 mg Tablets | - | 11/11/19 | 11/11/19 | sotalol hydrochloride | Gerard Laboratories |
| Sovaldi 400 mg film coated tablets | | 30/10/19 | 30/10/19 | Sofosbuvir | Gilead Sciences Ltd |
| Spasmonal 60mg hard capsules | - | 24/05/19 | 28/09/18 | Alverine Citrate | Mylan IRE Healthcare Limited |
| Spasmonal Forte 120mg hard capsules | - | 24/05/19 | 28/09/18 | Alverine Citrate | Mylan IRE Healthcare Limited |
| Spedra 50 mg, 100 mg and 200 mg tablets | - | 01/08/19 | 01/08/19 | Avanafil | A. Menarini Pharmaceuticals Ireland Ltd |
| Spinraza 12 mg solution for injection | | 31/01/20 | 31/01/20 | Nusinersen sodium | Biogen Idec Ltd |
| Spiolto Respimat 2.5 microgram/2.5 microgram, inhalation solution | | 02/12/19 | 02/12/19 | Olodaterol hydrochloride, Tiotropium bromide monohydrate | Boehringer Ingelheim Limited |
| Spiriva | - | 14/01/19 | 14/01/19 | Tiotropium bromide monohydrate | Boehringer Ingelheim Limited |
| Spiriva Respimat 2.5 microgram, inhalation solution | - | 02/12/19 | 02/12/19 | Tiotropium bromide monohydrate | Boehringer Ingelheim Limited |
| Sporanox 10 mg/ml oral solution | - | 12/04/19 | 12/04/19 | Itraconazole | Janssen Sciences Ireland |
| Sporanox 100mg Capsules | - | 12/04/19 | 12/04/19 | Itraconazole | Janssen Sciences Ireland |
| Sprycel 10 mg/mL powder for oral suspension | - | 04/07/19 | 04/07/19 | dasatinib monohydrate | Bristol-Myers Squibb Pharma EEIG |
| Sprycel 20mg, 50mg, 70mg and 100mg Film-Coated Tablets | - | 02/07/19 | 02/07/19 | dasatinib monohydrate | Bristol-Myers Squibb Pharma EEIG |
| Stalevo 100 mg/25 mg/200 mg film-coated tablets | - | 06/09/19 | 06/09/19 | Carbidopa, Entacapone, Levodopa | Orion Pharma (Ireland) Ltd |
| Stalevo 125 mg/31.25 mg/200 mg film-coated tablets | - | 06/09/19 | 06/09/19 | Carbidopa, Entacapone, Levodopa | Orion Pharma (Ireland) Ltd |
| Stalevo 150 mg/37.5 mg/200 mg film-coated tablets | - | 06/09/19 | 06/09/19 | Carbidopa, Entacapone, Levodopa | Orion Pharma (Ireland) Ltd |
| Stalevo 175 mg/43.75 mg/200 mg film-coated tablets | - | 06/09/19 | 06/09/19 | Carbidopa, Entacapone, Levodopa | Orion Pharma (Ireland) Ltd |
| Stalevo 200 mg/50 mg/200 mg film-coated tablets | - | 06/09/19 | 06/09/19 | Carbidopa, Entacapone, Levodopa | Orion Pharma (Ireland) Ltd |
